I've used it on my firearms before. Its decent stuff. As far as using it on an airbrush... I don't think it will hurt anything, but I doubt you will see much difference between the Frog lube and the airbrush specific stuff, like Needle Juice. I've used lots of different things on my needle, from synthetic automotive oils, to gun oils, to all the airbrush specific products. I really can't tell much of a difference between any of them. They all keep things moving nice and smooth, and they all wipe off the tip of the needle within the first couple of minutes of a painting session as you remove tip dry. This stuff is supposed to work its way into the microscopic ridges in the metal, or something like that, if I remember correctly. I don't know how that is any different from any other high quality lubricant, so sounds like a marketing strategy to me, but there is nothing about the product that should hurt your airbrush.