See, the logic is starting to kick in, if you're mixing in the brush always add the reducer (water in this case) first. then add paint. Backflush to mix, remembering to put the lid on or at least cover it with the palm of your hand.
By being methodical at this stage it will help lessen the stress, minimise the variables.
so you currently have 2:1 working well at 18 psi (with what brush)
That formula will probably not work with the other brushes. This is why we often tell newbies to pick 1 brush, 1 brand of paint and learn to figure out the sweet spot so you can spray consistently and therefor have more fulfilling practise.
Once you have the basics done, then you can gradually add new variables eg, keep the same formula but change the brush - you'll be surprised at the difference
.
and as Marcos says, start cleaning the tip regularly, you'll start to just 'know' when it needs cleaning, the paint will spray different, it will sound different.
again, its frustrating but all part of the learning